Skip to main content

Risks of Mixing Alcohol and Prescription Medication

The risks of mixing alcohol and prescription medication can be severe. Most prescription medications come with a label stating to avoid alcohol consumption when taking the medication. This is due to the effects that alcohol can have on the effects of the medication. Using prescription medications and drinking alcohol can lead to the effects of either substance heightening leading to complications and side effects that can be unpredictable and dangerous. 

Stats of Mixing Alcohol and Prescription Medication

Mixing alcohol and prescription medication is a dangerous risk to take. Nearly 50% of overdose deaths in 2019 involved more than one substance, according to the Centers for Disease Control and Prevention (CDC).

Alcohol is a depressant and using it in combination with other drugs can cause negative effects. It can increase the risk of heart, brain, and other organ damage. It can also lead to overdose and death. The effects that alcohol can have on prescription medications can be extremely unpredictable and vice versa. The side effects of any given medication can be heightened, or altered when they are mixed with 12>alcohol.

Dangers of Mixing Alcohol and Prescription Medication

Knowing the dangers of mixing alcohol and prescription medication is vital to preventing severe complications in those who take medications and drink alcoholic beverages. Alcohol alone can be extremely dangerous, and when it is mixed with prescription medications, the results can be unpredictable and lead to severe health complications. The respiratory depression that can result from using alcohol can be exacerbated when mixing alcohol and prescription medications.

It can also lead to damage in vital organs that are necessary for body functionality like the liver and the heart. Damage to these organs can be irreversible and lead to severe health complications. When mixing alcohol and prescription medications it can cause impaired judgment that leads to actions that are out of character for an individual. This can include driving under the influence, leading to accidents and injury.

Effects of Mixing Alcohol and Prescription Medication

The effects that can be experienced when mixing alcohol and prescription medication can be intense. Depressants like Xanax and Valium have effects that include respiratory depression and drowsiness. When mixed with alcohol, these symptoms and effects of depressants like 12>benzos can be heightened.

When the respiratory system is severely depressed, it can lead to a lack of oxygen intake. Oxygen is crucial to the proper functioning of the organs within the body. When oxygen is lacking it can lead to hypoxemia. Hypoxemia is a life-threatening condition that can lead to organ failure and death. Mixing alcohol and prescription medication is extremely dangerous, and can be fatal.

Risk Factors of Mixing Alcohol and Prescription Medication

The risk factors can be extreme. Alcohol is dangerous on its own, and so are prescription medications. When mixing the two it can make the effects exacerbated and lead to severe health complications. It can also lead to dependence on the substances being used.

When the effects of mixing alcohol with prescription medication are altered, it can result in using more and more of the substances. When the level of use is higher, the body becomes tolerant to those levels of use, leading to the body requiring higher and higher doses of the substances in order to achieve the desired effects. Using more and more can often lead to addiction to these substances.

When addiction occurs and a person tries to stop using alcohol or medications, it can lead to severe and uncomfortable withdrawal symptoms. This makes detox necessary in order to remove the substances from the body and begin the process of recovery.

Detox for Polysubstance Abuse

Mixing alcohol and 12>prescription medication can lead to complications when it comes to detox. Polysubstance abuse is a dangerous undertaking for anyone who is going through it. Using alcohol and other substances together can be difficult to overcome. However, it is possible.

Detox is the beginning step to getting better. Ridding the body of the toxins introduced through substance misuse is necessary for recovery. Once the body is free and clear of harmful substances, healing, and recovery can begin for those who are struggling.

Common withdrawal symptoms during detox can include the following:

  • Sleep disturbances
  • Muscle aches and cramps
  • High or low blood pressure
  • Increased appetite
  • Nausea, vomiting, and diarrhea

Sometimes, these withdrawal symptoms can lead to complications in health. This is why it is highly recommended and suggested to have professional assistance as someone is going through this process. This helps to prevent complications that could potentially be life-threatening.

Getting Better in Louisville, KY

Mixing alcohol and prescription medications can be extremely dangerous. The effects of doing this can be unpredictable and life-threatening. Mixing alcohol with prescription medications can lead to complications that can include respiratory distress leading to a lack of oxygen to vital organs.

If you or a loved one are struggling with mixing alcohol and prescription medications, there is help available. At Louisville Addiction Center, we offer necessary help to those struggling with substances so that they can begin finding recovery. 12>Contact us today to start the process of getting better. 

→ Sources
  1. Alcohol Rehab Help. (2022). Alcohol statistics in Kentucky. Alcohol Rehab Help. https://alcoholrehabhelp.org/kentucky/alcohol-statistics/
  2. Healthy KY. (n.d.). Drug and alcohol statistics in Kentucky. Healthy Kentucky. https://www.healthyky.org/drug-and-alcohol-statistics-in-kentucky.html
  3. Kentucky Office of Drug Control Policy. (n.d.). An assessment of Kentucky’s substance use disorder crisis. Commonwealth of Kentucky. https://odcp.ky.gov/
  4. Kong, J. (2022). An assessment of alcohol use disorder and treatment [Research brief]. University of Louisville. https://louisville.edu/sphis/departments/cik/docs-and-pdfs-1/Kong_AUD_ResearchBrief_FINALADA.pdf
  5. Substance Abuse and Mental Health Services Administration. (2019). State profile: Kentucky—N-SSATS report. SAMHSA. https://www.samhsa.gov/data/sites/default/files/quick_statistics/state_profiles/NSSATS-KY19.pdf
  6. Substance Abuse and Mental Health Services Administration. (2024). Underage drinking prevention programs in Kentucky. SAMHSA. https://library.samhsa.gov/sites/default/files/kentucky-iccpud-state-report-2024.pdf
  7. Wikipedia. (2025). Casey’s Law (Matthew Casey Wethington Act). In Wikipedia. https://en.wikipedia.org/wiki/Casey%27s_Law
→ Contributors
Portrait of Dr. Vahid Osman, Board-Certified Psychiatrist and Addictionologist
Medically Reviewed By
Dr. Vahid Osman, M.D.
Board-Certified Psychiatrist & Addictionologist
Dr. Vahid Osman is a Board-Certified Psychiatrist and Addictionologist with extensive experience treating mental illness, chemical dependency, and developmental disorders. Dr. Osman trained in Psychiatry in France and in Austin, Texas. Read more.
Portrait of Josh Sprung, L.C.S.W.
Clinically Reviewed By
Josh Sprung, L.C.S.W.
Board-Certified Clinical Social Worker
Joshua Sprung serves as a Clinical Reviewer at Louisville Addiction Center, bringing a wealth of expertise to ensure exceptional patient care. Read more.
→ Accreditations & Licenses

Addiction Treatment

Drug and Alcohol Rehab | Louisville Addiction Center

Treatment Programs

Treatment Programs | Louisville Addiction Center

Mental Health Services

Primary Mental Health | Louisville Addiction Center

Areas We Serve

  • Fayette
  • Bowling Green
  • Owensboro
  • Covington
  • Georgetown
  • Richmond
  • Florence
  • Elizabethtown
  • Nicholasville
  • Hopkinsville
  • Jeffersontown
  • Independence
  • Frankfort
  • Henderson
  • Paducah
  • Radcliff
  • Ashland
  • Erlanger
  • Madisonville
  • Winchester
  • Burlington
  • Mount Washington
  • St. Matthews
  • Murray
  • Fort Thomas
  • Shelbyville
  • Danville
  • Shively
  • Berea

What Our Patients Say: Stories of Hope and Recovery

Real Testimonials

Hear directly from those who have walked the path to recovery. Our patients’ stories highlight the compassionate care, effective programs, and life-changing support they’ve experienced. Let their journeys inspire you as you take your first steps toward healing.

Austin B. profile pictureAustin B.
18:15 16 Mar 25
LAC was great. I participated in the evening groups through zoom, which I originally had reservations about. Even though the meetings were online, they were still very engaging, informative, and personal. The therapist and case manager were incredible. They were both very authentic and supportive, and they were easily available when we needed them. I am very appreciative and grateful for this program.
Coley W. profile pictureColey W.
15:47 02 Feb 25
I’ve had great success with the individuals i’ve sent to LAC. I’ve been impressed with the smooth Admissions process in the stressful situations. The compassion they receive after arriving and the level of care is as good as anywhere out there. Most definitely will continue to use LAC
Kyle T. profile pictureKyle T.
18:50 08 Aug 24
I have nothing but positive things to say about LAC. I went there not expecting too much and I left there with what feels like a family. Everyone is so nice and extremely down to earth. You will be in good hands at LAC
William S. profile pictureWilliam S.
02:56 18 Jul 24
This is 5 star facility. The staff is one of a kind, the program is exactly what you are looking for. Call these people today if you or someone you know is struggling!
Aaron A. profile pictureAaron A.
13:58 13 Jun 24
Great place with great staff that care!
Jacob W. profile pictureJacob W.
00:34 16 Apr 24
Would highly recommend LAC to anyone struggling with addiction. They offer a supportive environment that allows you to focus on your recovery and becoming a productive member of society.
Brad F. profile pictureBrad F.
19:37 24 Oct 23
LAC is an amazing treatment facility. Truly a 5 * place for treatment. From ownership, leadership to general staff this place is incredible. The therapist, Techs and speakers are all first class. The housing, if doing PHP like I participated in was also perfect. I met so many incredible people. It’s unreal to be honest. I today this day still stay in contact with most residents who I attended with. Thank you LAC for not only all of your help but also continued support!!!
Brad Franzman
Matt H. profile pictureMatt H.
13:36 20 Jul 23
Louisville addiction center is a wonderful facility for anyone struggling with substance use disorders. The staff is wonderful and client care is most important. If you or a loved one are struggling I would highly recommend this place.
Kathryn T. profile pictureKathryn T.
01:49 21 Mar 23
This is an awesome place for anyone struggling with a substance use disorder. It is a beautiful facility, conveniently located to all Louisville has to offer. The staff members are kind and helpful, it is easy to tell they truly want to help you recover. 10/10 recommend this programming if you are ready to make a change.
David W. profile pictureDavid W.
15:00 04 Mar 23
I had the opportunity to tour and attend the open house for Louisville Addiction Center on 2/22/23. As and individual in recovery and also working for SUD, I couldn’t be more impressed with the facility and approach that LAC is taking and offering those affected by substance abuse. If you or a loved one is struggling, this facility would provide the treatment, love and comfort your family member deserves.

Get Directions to Louisville Addiction Center